Occult ischemic necrosis of skeletal muscle.

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چکیده

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Occult ischaemic necrosis of skeletal muscle associated with renal failure.

Case reports Case I-A 61 year old man developed thrombosis in a right femoropopliteal bypass graft necessitating below knee amputation. There were no muscle symptoms or signs and no loss of pulsation in the remaining leg. Twenty four hours postoperatively he became oliguric, acidotic, and hyperkalaemic. Serum creatine kinase activity was >10000 U/I (normal <190 U/1). He developed oliguric renal...

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Skeletal Muscle – Necrosis

Figure Legend: Figure 1 Skeletal muscle Necrosis in a male F344/N rat from a chronic study. This cross section of skeletal muscle exhibits an extensive, highly fragmented and vacuolated collection of muscle fibers; some are hypereosinophilic, and others are pale. Figure 2 Skeletal muscle Necrosis in a male F344/N rat from a chronic study. Dystrophic mineralization has affected several necrotic ...

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Nitric Oxide is Necessary for Diazoxide Protection Against Ischemic Injury in Skeletal Muscle

Ischemia reperfusion injury (IR injury) is a common problem in clinical conditions. Researches have frequently revealed that ATP- sensitive potassium (KATP) channels and nitric oxide plays a role in protection against ischemic injury in skeletal muscle. The present study aimed at evaluating the possible link between this two pathways. Sixty-eight male wistar rats, were pretreated with saline, d...

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Nitric Oxide is Necessary for Diazoxide Protection Against Ischemic Injury in Skeletal Muscle

Ischemia reperfusion injury (IR injury) is a common problem in clinical conditions. Researches have frequently revealed that ATP- sensitive potassium (KATP) channels and nitric oxide plays a role in protection against ischemic injury in skeletal muscle. The present study aimed at evaluating the possible link between this two pathways. Sixty-eight male wistar rats, were pretreated with saline, d...

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Muscle metaboreflex improves O2delivery to ischemic active skeletal muscle.

Ischemia of active skeletal muscle elicits a powerful pressor response, termed the muscle metaboreflex. We recently reported that the muscle metaboreflex pressor response acts to partially restore blood flow to the ischemic active skeletal muscle. However, because this reflex is activated by reductions in O2 delivery rather than blood flow per se, gain of the muscle metaboreflex as analyzed on ...

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ژورنال

عنوان ژورنال: BMJ

سال: 1990

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.301.6752.610-b